Article 11420

Title of the article



Evdokimov Sergey Vasilievich, Candidate of engineering sciences, executive manager, Research and Production Enterprises “MedEng” (1 Tsentralnaya street, Penza, Russia), E-mail:
Evdokimov Alexander Sergeevich, Candidate of engineering sciences, director of “MedIntell” LLC (1 Tsentralnaya street, Penza, Russia), E-mail:
Muyzemnek Aleksandr Yur'evich, Doctor of engineering sciences, professor, head of the sub-department of theoretical and applied mechanics and graphics, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: 

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616-77: 611.126 




Background. About half of heart valve prosthetics are mechanical prostheses. Mechanical prostheses of heart valves have several advantages over biological ones. Nevertheless, there are also the negative consequences of their implantation include blood hemolysis and platelet activation. The purpose of the work was to create adequate computer models of hemodynamics of the “MedEng-ST” full-flow heart valve, allowing estimating the number of destroyed red blood cells, activated platelets and the tendency of the course to develop cavitation in it
Materials and methods. The process of blood flow through the “MedEng-ST” full-flow heart valve, installed in the aortic position, during systole was considered. The hydrodynamic characteristics of the flow were determined by computational fluid dynamics methods using the ANSYS/CFX program. Original models were used to determine the number of destroyed erythrocytes and activated platelets.
Results. A numerical model has been developed and the hemodynamics of the “MedEng-ST” full-flow heart valve has been simulated, because of which the relative content of destroyed red blood cells and the tendency of the flow to develop cavitation in it are estimated.
Conclusions. It was found that during systole, relatively high concentrations of destroyed red blood cells are present in local areas of the calculated area; their values do not exceed 0.01 %. The average over the area of the output section values of the relative number of destroyed red blood cells do not exceed 3·10–6 %. The propensity of the flow to develop cavitation in it has not been identified. 

Key words

“MedEng-ST” full-flow heart valve, hemodynamics, hemolysis, computer model, the destruction of red blood cells, platelet activation, cavitation 

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Дата создания: 20.01.2021 09:52
Дата обновления: 20.01.2021 11:08